Serially remembered items are successively reactivated during memory maintenance in the human brain, and replay profiles, temporally compressed and reverse in order, are associated with recency effect in behavioral performance.
By moving from correlations to causality in cancer signal transduction using optogenetics, the sufficiency of RalB activation to trigger invasion and the underlying molecular mechanisms were established.
New germline gene expression, knockout, and optogenetic tools reveal essential roles for Gα-GPR-1,2/Pins as a regulatable membrane anchor and LIN-5/NuMA as an activator of cortical dynein in mitotic spindle positioning.
Simultaneous EEG-fMRI reveals neural representations of decision confidence unfolding prior to explicit perceptual choices, in a region of the ventromedial prefrontal cortex typically linked to reward processing and value-based decisions.
The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.