Imaging experiments reveal that some brain regions do not distinguish between actions performed using tools and those performed using the hands, while others represent these two types of action separately.
Tamar R Makin, Alona O Cramer ... Heidi Johansen-Berg
In individuals with a missing hand, the area of the brain that would otherwise control that hand is recruited by either the remaining hand or the residual limb, depending on the usage preference of the individual.
An area of visual-motor cortex called the lateral intraparietal area encodes eye position signals that support visually-guided behaviors and image stabilization.
Debashree Chatterjee, Richard B Cooley ... Holger Sondermann
Structure-function analyses reveal the mechanistic underpinnings of inside-out transmembrane signaling that controls periplasmic proteolysis, and thereby biofilm formation, in bacteria and may be relevant in the context of other signaling proteins with similar control elements.
Avital Hahamy, Stamatios N Sotiropoulos ... Tamar R Makin
Building on previous work (Makin et al., 2013), we show that the brains of individuals born without a hand adaptively change to compensate for their disability.
Matthew T Kaufman, Mark M Churchland ... Krishna V Shenoy
Trial-by-trial analysis of neuronal activity in monkeys performing a decision-making task reveals the neural correlates of behaviours including wavering, hesitation and sudden changes of mind.
Chethan Pandarinath, Vikash Gilja ... Krishna V Shenoy
Neural ensemble activity in the human motor cortex contains dynamical structure that is independent of movement parameters and is not well-explained by current models.
Viktoria Désirée Paul, Ulrich Mühlenhoff ... Roland Lill
Two newly identified assembly factors for the ribosome-associated iron-sulfur protein Rli1 reveal a general mechanism for how the cytosolic iron-sulfur protein assembly (CIA) machinery recruits apoproteins.