110 results found
    1. Neuroscience

    Decoding the neural mechanisms of human tool use

    Jason P Gallivan, D Adam McLean ... Jody C Culham
    Imaging experiments reveal that some brain regions do not distinguish between actions performed using tools and those performed using the hands, while others represent these two types of action separately.
    1. Neuroscience

    Deprivation-related and use-dependent plasticity go hand in hand

    Tamar R Makin, Alona O Cramer ... Heidi Johansen-Berg
    In individuals with a missing hand, the area of the brain that would otherwise control that hand is recruited by either the remaining hand or the residual limb, depending on the usage preference of the individual.
    1. Neuroscience

    Inferring eye position from populations of lateral intraparietal neurons

    Arnulf BA Graf, Richard A Andersen
    An area of visual-motor cortex called the lateral intraparietal area encodes eye position signals that support visually-guided behaviors and image stabilization.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Mechanistic insight into the conserved allosteric regulation of periplasmic proteolysis by the signaling molecule cyclic-di-GMP

    Debashree Chatterjee, Richard B Cooley ... Holger Sondermann
    Structure-function analyses reveal the mechanistic underpinnings of inside-out transmembrane signaling that controls periplasmic proteolysis, and thereby biofilm formation, in bacteria and may be relevant in the context of other signaling proteins with similar control elements.
    1. Neuroscience

    Normalisation of brain connectivity through compensatory behaviour, despite congenital hand absence

    Avital Hahamy, Stamatios N Sotiropoulos ... Tamar R Makin
    Building on previous work (Makin et al., 2013), we show that the brains of individuals born without a hand adaptively change to compensate for their disability.
    1. Neuroscience

    Vacillation, indecision and hesitation in moment-by-moment decoding of monkey motor cortex

    Matthew T Kaufman, Mark M Churchland ... Krishna V Shenoy
    Trial-by-trial analysis of neuronal activity in monkeys performing a decision-making task reveals the neural correlates of behaviours including wavering, hesitation and sudden changes of mind.
    1. Medicine
    2. Neuroscience

    Neural population dynamics in human motor cortex during movements in people with ALS

    Chethan Pandarinath, Vikash Gilja ... Krishna V Shenoy
    Neural ensemble activity in the human motor cortex contains dynamical structure that is independent of movement parameters and is not well-explained by current models.
    1. Structural Biology and Molecular Biophysics
    2. Plant Biology

    The structure of plant photosystem I super-complex at 2.8 Å resolution

    Yuval Mazor, Anna Borovikova, Nathan Nelson
    The crystal structure of higher plant PSI-LHCI complex reveals intricate details responsible for light harvesting.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The deca-GX3 proteins Yae1-Lto1 function as adaptors recruiting the ABC protein Rli1 for iron-sulfur cluster insertion

    Viktoria Désirée Paul, Ulrich Mühlenhoff ... Roland Lill
    Two newly identified assembly factors for the ribosome-associated iron-sulfur protein Rli1 reveal a general mechanism for how the cytosolic iron-sulfur protein assembly (CIA) machinery recruits apoproteins.

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