177 results found
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis

    Kira Breunig, Xuifen Lei ... Luiz O Penalva
    SERBP1 is associate with protein complexes regulating splicing, cell division, and ribosomal biogenesis that likely depend on G quadruplex (G4) binding and polyADP-ribosylation (PARylation) for their assembly and function.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structure of METTL3-METTL14 with an m6A nucleotide reveals insights into m6A conversion and sensing

    Shan Qi, Abhay Kumar ... Yogesh K Gupta
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cancer Biology

    Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab resistant HER2 positive breast cancer

    Yijia Hua, Ningjun Duan ... Yongmei Yin
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Cell Biology
    2. Cancer Biology

    N6-methyladenosine in DNA promotes genome stability

    Brooke A Conti, Leo Novikov ... Mariano Oppikofer
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    Coordinated regulation of chemotaxis and resistance to copper by CsoR in Pseudomonas putida

    Meina He, Yongxin Tao ... Wenli Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Microbiology and Infectious Disease

    Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria

    Yogita Kapoor, Himani Khurana ... Vinay Kumar Nandicoori
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Genetics and Genomics

    Mettl5 coordinates protein production and degradation of PERIOD to regulate sleep in Drosophila

    Xiaoyu Wu, Xingzhuo Yang ... Juan Du
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    Maintenance of neuronal TDP-43 expression requires axonal lysosome transport

    Veronica H Ryan, Sydney Lawton ... Michael E Ward
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    The Role of ATP Synthase Subunit e (ATP5I) in Mediating the Metabolic and Antiproliferative Effects of Biguanides

    Guillaume Lefrançois, Emilie Lavallée ... Gerardo Ferbeyre
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology

    In silico screening by AlphaFold2 program revealed the potential binding partners of nuage-localizing proteins and piRNA-related proteins

    Kawaguchi Shinichi, Xu Xin ... Kai Toshie
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
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