Eric Kenji Lee, Hymavathy Balasubramanian ... Chandramouli Chandrasekaran
WaveMAP is a novel approach that combines nonlinear dimensionality reduction with graph clustering on extracellular waveforms to reveal previously obscured cell type diversity in monkey cortex.
Thomas P Spargo, Lachlan Gilchrist ... Alfredo Iacoangeli
Pleiotropic loci that play a role in multiple neuropsychiatric diseases exist, but many of them might contribute to each disease via a distinct mechanism.
Birds that see ultraviolet light tune the sensitivity of their short-wavelength photoreceptors with colored filters to maximize the number of colors they can see.
Flavio H Beraldo, Daniel Palmer ... Marco AM Prado
Comprehensive dataset of high-level cognitive assessment in mouse models of neurodegeneration, accompanied by an open-access database/repository to change the paradigm of how cognitive studies in animal models can be shared/re-used.
Computational simulations of actin network growth at the cell leading edge, combined with careful high-speed video microscopy measurements of leading edge shape fluctuations, suggest that Arp2/3 branching of the actin network occurs at an optimal angle to minimize fluctuations.
Shreya H Dhume, Steven A Connor ... Tabrez J Siddiqui
LRRTM1 and LRRTM2 play multifaceted roles in the molecular organization of neuronal circuits through mediating context-dependent functions in synapse development but independent roles in plasticity and cognition.
Pedro Sampaio, Sara Pestana ... Susana Santos Lopes
Zebrafish have a physiological time-window of 1 hr for breaking left-right symmetry and are highly sensitive to the left-right organizer anterior fluid mechanics rather than to the nature of its fluid content.
Benoit Ballester, Alejandra Medina-Rivera ... Michael D Wilson
Combinatorial transcription factor binding shared by multiple species enriches for essential biological pathways and coincides with disease-causing regulatory DNA mutations.