3,282 results found
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Protein kinase C coordinates histone H3 phosphorylation and acetylation

    Zoulfia Darieva et al.
    Chromatin structure is altered following DNA replication stress through the activity of protein kinase C signalling which leads to functionally coupled histone H3 phosphorylation and acetylation events.
    1. Neuroscience

    Protein kinase C is a calcium sensor for presynaptic short-term plasticity

    Diasynou Fioravante et al.
    Genetic and electrophysiology experiments provide the first direct evidence that protein kinase C is a calcium-sensing protein in post-tetanic potentiation, a form of synaptic plasticity that supports short-term memory.
    1. Microbiology and Infectious Disease

    Influenza virus recruits host protein kinase C to control assembly and activity of its replication machinery

    Arindam Mondal et al.
    Host protein kinase C family members regulate influenza virus genome replication by phosphorylating the viral nucleoprotein and controlling assembly of the viral replication machinery.
    1. Chromosomes and Gene Expression
    2. Human Biology and Medicine

    A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome

    Jefferson J Doyle et al.
    Calcium channel blockers accelerate aortic aneurysm and cause premature aortic rupture in a mouse model of Marfan syndrome through protein kinase C-mediated activation of extracellular signal-regulated kinase.
    1. Neuroscience

    Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release

    Özgür Genç et al.
    Protein kinase C brings about post-tetanic potentiation - a temporary increase in synaptic strength due to increased transmitter release - via phosphorylation of a target protein, Munc18-1.
    1. Microbiology and Infectious Disease

    The c-Jun N-terminal kinase pathway of a vector insect is activated by virus capsid protein and promotes viral replication

    Wei Wang et al.
    Plant viruses enhance their replication in vector insects by activating the vector's JNK pathway, and inhibition of this pathway may be a useful strategy for controlling transmission of plant viruses.
    1. Neuroscience

    Self-organization of modular network architecture by activity-dependent neuronal migration and outgrowth

    Samora Okujeni, Ulrich Egert
    Activity-dependent neurite outgrowth and neuronal migration interact to shape modular mesoscale network architecture by homeostatic self-organization.
    1. Neuroscience

    A longitudinal study of Caenorhabditis elegans larvae reveals a novel locomotion switch, regulated by Gαs signaling

    Stanislav Nagy et al.
    C. elegans exhibits two distinct behavioural macro-states, active and quiet wakefulness, and protein kinase A regulates switching between these two states.
    1. Neuroscience

    AMPK acts as a molecular trigger to coordinate glutamatergic signals and adaptive behaviours during acute starvation

    Moloud Ahmadi, Richard Roy
    AMP-activated protein kinase directly coordinates glutamatergic signalling during starvation in C. elegans.

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