7,221 results found
    1. Cell Biology

    ScRNA-seq and scATAC-seq reveal that sertoli cell mediate spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia

    Shimin Wang, Hongxian Wang ... Dong Zhao
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    • Incomplete
    1. Cell Biology

    Novel Mechanism for Tubular Injury in Nephropathic Cystinosis

    Swastika Sur, Maggie Kerwin ... Minnie M Sarwal
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics

    Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling

    Nevin K Zacharia, Stefanie Kuhns ... Esben Lorentzen
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state

    Ruben Sebastian-Perez, Shoma Nakagawa ... Maria Pia Cosma
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    • Incomplete
    1. Genetics and Genomics
    2. Cancer Biology

    Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer

    Tackhoon Kim, Byung-Sun Park ... Timothy K Lu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Developmental Biology

    Endosomal-lysosomal organellar assembly (ELYSA) structures coordinate lysosomal degradation systems through mammalian oocyte-to-embryo transition

    Yuhkoh Satouh, Takaki Tatebe ... Ken Sato
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Flexibility in PAM Recognition Expands DNA Targeting in xCas9

    Kazi A Hossain, Lukasz Nierzwicki ... Giulia Palermo
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Structural Biology and Molecular Biophysics

    Simulation-based survey of TMEM16 family reveals that robust lipid scrambling requires an open groove

    Christina A Stephens, Niek van Hilten ... Michael Grabe
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Inadequate
    1. Cell Biology

    Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Fertility

    Takahiro Yamanaka, Zimo Xiao ... Masayuki Shimada
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics

    Expanding Automated Multiconformer Ligand Modeling to Macrocycles and Fragments

    Jessica Flowers, Nathaniel Echols ... Stephanie A Wankowicz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
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