Using genetics, it is possible to uncouple higher adiposity from its adverse metabolic effects and show that some obesity-associated conditions may benefit from treating the metabolic effects alone, whilst others may benefit more from weight loss.

Numerous related sample characteristics affect polygenic score performance, and incorporation of interaction effects increases both model and polygenic score performance.

The fabled land of Punt is mapped for the first time using quantitative methods from the disciplines of primatology, geochemistry, and geography.

Many of the effects of intelligence on health and social outcomes later in life are mediated via education.

People who have attempted suicide exhibit blunted sensory processing during breathing and pain perturbations, as well as lower heartbeat perception accuracy and reduced mid/posterior insula activity during interoceptive attention.

Intersectin2 deficiency is associated with impaired humoral responses to viral infection and B-cell-intrisic defects in germinal centre formation, resulting from the reduced ability of intersectin2-KO B cells to establish cognate interactions with helper T cells.

The proposed techniques enable researchers to disentangle the statistical features of neural population responses, and rigorously quantify how these features carry information about stimuli and experimental variables.

A new Bayesian algorithm for tracking subjects’ choice strategies on every trial reveals when subjects learn and what they tried while doing so, providing strong evidence that reward- and loss-driven exploration change independently.