535 results found
    1. Microbiology and Infectious Disease

    Cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis

    Junghoon Lee, Scot P Ouellette
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Microbiology and Infectious Disease

    ATP burst is the dominant driver of antibiotic lethality in Mycobacterium smegmatis

    Tejan Lodhiya, Aseem Palande ... Raju Mukherjee
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics

    Wide Transition-State Ensemble as Key Component for Enzyme Catalysis

    Gabriel Ernesto Jara, Francesco Pontiggia ... Dorothee Kern
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments

    Sofia Lövestam, Jane L Wagstaff ... Sjors HW Scheres
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Solid
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration

    Ana Patrícia Graça, Vadim Nikitushkin ... Gerald Lackner
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Immunology and Inflammation

    B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size

    Sung Hoon Cho, Marissa A Jones ... Mark R Boothby
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification

    Louna Fruchard, Anamaria Babosan ... Zeynep Baharoglu
    tRNA Q34 modification impacts tyrosine codon decoding and leads to proteome reprogramming in response to antibiotic stress in Vibrio cholerae.
    1. Plant Biology

    A florigen-expressing subpopulation of companion cells expresses other small proteins and reveals a nitrogen-sensitive FT repressor

    Hiroshi Takagi, Shogo Ito ... Takato Imaizumi
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Microbiology and Infectious Disease

    Magnesium modulates phospholipid metabolism to promote bacterial phenotypic resistance to antibiotics

    Hui Li, Jun Yang ... Bo Peng
    Dysregulated unsaturated fatty acids and saturated fatty acids contribute to bacterial phenotypic resistance to antibiotics.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The fate of pyruvate dictates cell growth by modulating cellular redox potential

    Ashish G Toshniwal, Geanette Lam ... Jared Rutter
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
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