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    1. Developmental Biology

    An autoregulatory cell cycle timer integrates growth and specification in chick wing digit development

    Joseph Pickering, Kavitha Chinnaiya, Matthew Towers
    A cell cycle timing mechanism similar to one operating in cultured adult oligodendrocyte progenitor cells controls the growth and patterning of the embryonic chick wing bud.
    1. Plant Biology

    Active suppression of a leaf meristem orchestrates determinate leaf growth

    John Paul Alvarez, Chihiro Furumizu ... John L Bowman
    A meristem acting at the margins of Arabidopsis leaves is suppressed by factors acting primarily in leaves and other determinate organs.
    1. Developmental Biology
    2. Evolutionary Biology

    A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle

    Glenda Comai, Eglantine Heude ... Shahragim Tajbakhsh
    Tbx1-Isl1-Met defines a unique genetic hierarchy that regulates esophagus myogenesis and patterning in the mouse.
    1. Developmental Biology

    Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural crest cells condensation and outflow tract septation

    Jean-François Darrigrand, Mariana Valente ... Bruno Cadot
    New views on the relevance of bone morphogenetic protein signalling fine tuning in the cardiac neural crest cells for the heart outflow tract septation and the formation of the great arteries.
    1. Developmental Biology

    Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage

    Marketa Kaucka, Tomas Zikmund ... Igor Adameyko
    The clonal oriented cell dynamics enables directional expansion and accurate scaling of sheet-like or rod-like cartilaginous elements and uncouples the mechanisms of elongation from thickness or diameter control.
    1. Neuroscience

    The subiculum is a patchwork of discrete subregions

    Mark S Cembrowski, Lihua Wang ... Nelson Spruston
    Pyramidal cells of the subiculum, a major output cell type of the hippocampus, can be deconstructed into distinct subtypes that exhibit a patchwork-like organization in space.
    1. Developmental Biology
    2. Neuroscience

    Genetic specification of left–right asymmetry in the diaphragm muscles and their motor innervation

    Camille Charoy, Sarah Dinvaut ... Valerie Castellani
    Analysis of embryonic mouse diaphragm reveals muscle and nerve left–right asymmetries set by a Nodal-dependent genetic cascade, which imprints different molecular signatures to left and right motoneurons that shape their innervation pattern.
    1. Developmental Biology

    Cellular interpretation of the long-range gradient of Four-jointed activity in the Drosophila wing

    Rosalind Hale, Amy L Brittle ... David Strutt
    Opposing gradients of Fat and Dachsous phosphorylation are sufficient to explain the observed pattern of Fat-Dachsous planar polarisation across the Drosophila wing.
    1. Developmental Biology
    2. Neuroscience

    Protocadherin-dependent dendritic self-avoidance regulates neural connectivity and circuit function

    Dimitar Kostadinov, Joshua R Sanes
    Patterning of dendrites by protocadherin-dependent self-avoidance and self/non-self discrimination is required for proper function of a retinal circuit that computes the direction of motion.
    1. Developmental Biology

    Transgenic quails reveal dynamic TCF/β-catenin signaling during avian embryonic development

    Hila Barzilai-Tutsch, Valerie Morin ... Olivier Serralbo
    A novel avian transgenic line allows studying the function of Wnt signaling during embryonic development.