3 results found
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses

    Sevim Kahraman, Kimitaka Shibue ... Rohit N Kulkarni
    Live human pancreatic α-cells can be purified effectively using zinc-based reaction probe diacetylated Zinpyr1 and cultured as pseudoislets without losing their viability and function.
    1. Cell Biology

    P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian β-cell failure

    Biliana Marcheva, Benjamin J Weidemann ... Joseph Bass
    A genetically sensitized drug screen identifies a circadian diabetes target and establishes a novel discovery pathway to treat β-cell failure.
    1. Cell Biology
    2. Developmental Biology

    Tead1 reciprocally regulates adult β-cell proliferation and function to maintain glucose homeostasis

    Jeongkyung Lee, Ruya Liu ... Vijay K. Yechoor
    Not revised
    Reviewed Preprint v1

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