2 results found
    1. Biochemistry and Chemical Biology

    A dynamic RNA loop in an IRES affects multiple steps of elongation factor-mediated translation initiation

    Marisa D Ruehle et al.
    During initiation factor-independent RNA structure-driven translation initiation, a flexible RNA element drives the movement of a viral IRES through the ribosome's tRNA binding sites and promotes tRNA binding.
    1. Biochemistry and Chemical Biology

    Kinetics of initiating polypeptide elongation in an IRES-dependent system

    Haibo Zhang et al.
    The retarding effect of a ribosome-bound internal ribosome entry site on eukaryotic protein synthesis is largely overcome following translocation of tripeptidyl-tRNA.

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