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    1. Neuroscience

    Individuals with anxiety and depression use atypical decision strategies in an uncertain world

    Zeming Fang, Meihua Zhao ... Ru-Yuan Zhang
    A model with a mixture of three different decision strategies is developed to characterize several atypical behavioral patterns of individuals with depression and anxiety in an uncertain reward environment.
    1. Computational and Systems Biology
    2. Neuroscience

    Computational modeling of threat learning reveals links with anxiety and neuroanatomy in humans

    Rany Abend, Diana Burk ... Bruno B Averbeck
    Applying computational modeling to quantify threat learning processes uncovers how variations in these conserved learning processes relate to anxiety severity and the neuroanatomical substrates moderating these associations.
    1. Neuroscience

    Synaptic location is a determinant of the detrimental effects of α-synuclein pathology to glutamatergic transmission in the basolateral amygdala

    Liqiang Chen, Chetan Nagaraja ... Hong-Yuan Chu
    A combination of physiological, histological, and optical approaches reveals synapse-specific function of α-synuclein in mouse brain under both normal and pathological states.
    1. Neuroscience

    An observational treatment study of metacognition in anxious-depression

    Celine Ann Fox, Chi Tak Lee ... Claire M Gillan
    Improvement in levels of anxious-depression corresponds with increased confidence in performance among individuals receiving mental health treatment within a large longitudinal dataset.
    1. Neuroscience

    Unraveling the developmental dynamic of visual exploration of social interactions in autism

    Nada Kojovic, Sezen Cekic ... Marie Schaer
    Children with ASD showed a significant divergence in gaze patterns compared to typically developing children, intensifying over early childhood, with implications for developmental and adaptive functioning.
    1. Epidemiology and Global Health
    2. Medicine

    Investigating the relationship of COVID-19 related stress and media consumption with schizotypy, depression, and anxiety in cross-sectional surveys repeated throughout the pandemic in Germany and the UK

    Sarah Daimer, Lorenz L Mihatsch ... Franziska Knolle
    The uncertainties of the pandemic and the restrictions on social life have a strong impact on mental well-being, and especially on the expression of schizotypal traits, which are further boosted by excessive media consumption.
    1. Epidemiology and Global Health
    2. Medicine

    Cardiovascular disease and subsequent risk of psychiatric disorders: a nationwide sibling-controlled study

    Qing Shen, Huan Song ... Unnur Valdimarsdóttir
    Patients diagnosed with a cardiovascular disease are at higher risk of psychiatric disorders, independent of familial factors shared between full siblings and comorbid conditions.
    1. Neuroscience

    Humans perseverate on punishment avoidance goals in multigoal reinforcement learning

    Paul B Sharp, Evan M Russek ... Eran Eldar
    Humans perseverate on previously instructed goals in a novel multigoal reinforcement learning task, and do this to a greater extent for punishment avoidance goals.
    1. Medicine
    2. Neuroscience

    Hemispheric divergence of interoceptive processing across psychiatric disorders

    Emily M Adamic, Adam R Teed ... Sahib Khalsa
    Asymmetric activation of the dysgranular mid-insula during interoceptive processing contributes to disrupted bodily awareness in individuals with anxiety, depression, and eating disorders.
    1. Epidemiology and Global Health

    Adverse childhood experiences and resilience among adult women: A population-based study

    Hilda Björk Daníelsdóttir, Thor Aspelund ... Unnur Anna Valdimarsdóttir
    Cumulative exposure to adverse childhood experiences is associated with lower adult resilience among women in a dose-dependent manner, independent of adult socioeconomic factors and social support, indicating that adult female resilience is consolidated in early life.