Layer 5 pyramidal neurons vary substantially in dendritic excitability between primary and secondary visual cortex, likely due to a counterintuitive amplifying effect of long apical dendrites.

First structural view of a substrate-bound PIKK (PI3K-related-kinase) by cryo-EM explains phosphorylation specificity toward a short amino-acid motif shared across the PIKK family and rationalizes PIKK auto-inhibition by regulatory domain.

When real ants confront the classical 'Ant-in-a-labyrinth' physics problem where a random walker traverses a percolated environment, they employ active extended sensing and collective cognition to outperform passive physical solutions.

A new methodology and protocol use automated brain imaging and task training technology to probe links between behavior and mouse cortical circuits.

The splicing factor RNP-6/PUF60 suppresses immunity by modulating host splicing and transcriptional responses to infection.

In stau^-mutants, the Hunchback boundary shifts posteriorly by 10% EL but shows comparable variability to that of the wild type in short time windows in nuclear cycle 14.

The global sleep homeostatic process tracks sleep-wake history by integrating local cortical neuronal activity over time and space, rather than directly reflecting changes in specific homeostatically regulated physiological variables.

Optogenetic activation of cortical GABAergic cells in macaques yields robust and reversible behavioral deficits.

Distinct brain states govern resting state functional architecture revealed by neurophysiologically defined simultaneous optic-fiber-based calcium recordings and task-free functional magnetic resonance imaging (fMRI) in rats.