Pupil-linked arousal dynamics are influenced more strongly by high-level internal belief states than by low-level sensory events during decision-making.
A direct relationship between pupil diameter and electrophysiological correlates of attention, sensory stimulus processing and target detection was observed demonstrating that arousal has a substantial influence on perceptual decision-making.
Ear canal EEG and pupillometry reveal disordered temporal processing in adults with normal hearing who struggle to understand conversations in noisy backgrounds.
Enhanced perceptual discrimination occurs when ongoing population activity in visual cortex is in a 'silent' mode in which neurons optimize information extraction.
Across species and domains of decision-making, pupil-linked phasic arousal predicts suppression biases in the accumulation of evidence leading up to a choice.
Humans supplement complex, resource-demanding strategies with simple heuristics for solving the exploration-exploitation dilemma, and noradrenaline functioning controls their utilisation.
Aberration correction using 3D microprinting in ultrathin microendoscopes allows two-photon imaging of large neuronal networks with homogeneously high spatial resolution and minimal invasiveness in the deep mouse brain.
An effective and reversible mouse glaucoma model that replicates the secondary glaucoma in human patients caused by silicone oil after retina surgeries presents significant neurodegeneration, and is suitable for neuroprotectants selection.
A novel single-objective light-sheet microscope with unparalleled spatiotemporal resolution enables imaging and optical manipulation of diverse biological specimens and processes.