Jan Willem de Gee, Konstantinos Tsetsos ... Tobias H Donner
Across species and domains of decision-making, pupil-linked phasic arousal predicts suppression biases in the accumulation of evidence leading up to a choice.
Tomomi Tsunematsu, Amisha A Patel ... Shuzo Sakata
Sub-second pontine waves functionally interact with hippocampal population activity in a state-dependent manner across sleep states, while brainstem ensemble dynamics exhibit slow, long-lasting state-predictive activity.
VIP-expressing cortical interneurons represent organism-level information about reward and punishment for local microcircuits to regulate local processing and plasticity.
Davide Reato, Raphael Steinfeld ... Alfonso Renart
In a forced-choice auditory discrimination task, mice are more accurate if neural activity in the auditory cortex in the pre-stimulus baseline is higher and more desynchronized, but only if the previous trial was an error.
A novel single-objective light-sheet microscope with unparalleled spatiotemporal resolution enables imaging and optical manipulation of diverse biological specimens and processes.
When the acquisition of reward becomes effortful, marmosets choose to work longer, delaying their harvest, but slow their movements, reducing energy consumption.
When visual stimuli are repeated, gamma oscillations in human early visual cortex and feedforward gamma synchronization across the visual system show stimulus-specific and persistent increases.
Electrophysiology and optogenetic circuit manipulation in the mouse visual system reveal that corticothalamic feedback and behavioral state both have robust modulatory, yet largely independent influences on thalamic responses to naturalistic movies.
Alexandre LS Filipowicz, Christopher M Glaze ... Joshua I Gold
Pupil-linked arousal dynamics are influenced more strongly by high-level internal belief states than by low-level sensory events during decision-making.