CD40-activated CD40L-mediated reverse signalling has strikingly opposite effects on the growth of excitatory and inhibitory neuron dendrites in the developing brain of mice.
New evidence challenges the long-held view that motor cortex lacks a fourth layer, and reveals that its circuitry resembles that of other cortical regions more than previously thought.
Layer 5 neuron apical tuft in mouse visual cortex display widespread, highly correlated calcium signals, with a strong and asymmetric coupling to somatic signals, independent of visual stimulation and locomotion.
Mirror neurons, including corticospinal neurons, in primary motor cortex of macaque monkeys, clearly dissociate between execution and observation of grasping actions while ventral premotor cortex (F5) maintains a similar representation.
The medial entorhinal cortex is important for spatial memory formation and matures from dorsal, where smaller spatial-scales are represented, to ventral, where larger spatial-scales are represented.
In motor cortex pyramidal neurons, diverse task-related signals are distributed throughout the dendritic arbor and compartmentalized by dendritic distance and branching.
NMDA receptors on PV+ interneurons mediate supralinear integration at feedback synapses from local pyramidal neurons, enabling competing networks to ‘lock’ onto salient inputs.
