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    1. Genetics and Genomics
    2. Neuroscience

    A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons

    Gha-Hyun J Kim, Han Mo ... Su Guo
    In vivo dopamine neuron imaging-based neuroprotective small molecule screen in larval zebrafish and mechanistic investigation using conditional CRISPR knockout and cell-type-specific RNA-seq analysis, coupled with cross-species analyses including human clinical data interrogation, uncover potential disease-modifying therapeutics for Parkinson's disease (PD).
    1. Neuroscience

    Hierarchy between forelimb premotor and primary motor cortices and its manifestation in their firing patterns

    Akiko Saiki-Ishikawa, Mark Agrios ... Andrew Miri
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Cerebellar Purkinje Cells Control Posture in Larval Zebrafish (Danio rerio)

    Franziska Auer, Katherine Nardone ... David Schoppik
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience
    2. Physics of Living Systems

    A Deep Learning Pipeline for Mapping in situ Network-level Neurovascular Coupling in Multi-photon Fluorescence Microscopy

    Matthew Rozak, James Mester ... Bojana Stefanovic
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Evolutionary Biology

    Biases of Principal Component Analysis (PCA) in Physical Anthropology Studies Require a Reevaluation of Evolutionary Insights

    Nima Mohseni, Eran Elhaik
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Structural Biology and Molecular Biophysics

    Ab initio prediction of specific phospholipid complexes and membrane association of HIV-1 MPER antibodies by multi-scale simulations

    Colleen Maillie, Jay Golden ... Marco Mravic
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Immunology and Inflammation

    Ly6G+Granulocytes-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis

    Priya Sharma, Raman Deep Sharma ... Dhiraj Kumar
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    A neurocomputational account of the link between social perception and social action

    Lisa M. Bas, Ian D. Roberts ... Anita Tusche
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Epidemiology and Global Health

    Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

    Kathryn E Tiedje, Qi Zhan ... Karen P Day
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites

    S. P. Maher, M. A. Bakowski ... D. E. Kyle
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
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