Evolutionary loss of foot muscle in a bipedal rodent shares similarities with skeletal muscle atrophy, which is typically considered a pathological response to injury or disease.

Genetic, biochemistry and modeling approaches reveal elements of a Turing-type reaction-diffusion system to control pattern formation in differentiating cyanobacterial filaments.

A novel 2D-to-3D human brain organoid protocol reveals the pivotal role of FGF8 signaling in driving regional patterning and cellular diversity, while also modulating genes crucial for both normal and pathological neural development.

Single-cell transcriptomics analysis identifies the dynamic activity of transcription factors at the onset of hematopoeitic stem and progenitor cells formation during embryonic development.

Time-lapse imaging and the modular recreation of host physiology reveal that alveolar epithelial cells, potential permissive infection sites for Mycobacterium tuberculosis, can restrict early bacterial growth via surfactant secretion.

The Notch signaling pathway can use its various ligands, receptors, and Fringe proteins to generate diverse intra- and intercellular signaling behaviors.

Molecular analysis paints a detailed picture of the distinctiveness and complexities of peripheral somatosensory neurons.

RNA-binding proteins use both translational activation and repression of key molecular determinants to post-mitotically sculpt the identity and connectivity of developing mouse neocortex in an area-specific manner.

Two zebrafish Keap1-paralogs are equally adept at electrophile-sensing but manifest divergent and co-regulatory electrophile-signaling behaviors.

Adult stem cells acquire increased DNA damage as they migrate to a wound site and require active DNA repair mechanisms for normal migration.