Crowding and metabolites in a simulated cellular environment alter protein conformations, modulate interactions of functionally related proteins, and lead to significant dynamic heterogeneity.

The helical rod structure and dynamic spring-like properties of the type 1 pilus are evolutionarily fine-tuned for functioning in host-pathogen interactions during urinary tract infection and gut colonization.

An analysis of more than 70,000 journal articles, including 5405 that were first released as a preprint on bioRxiv, shows that articles with a preprint received 49% more attention and 36% more citations than articles without one.

Analysis of data on drug-gene interactions suggests that decentralized collaboration will increase the robustness of scientific findings in biomedical research.

Simultaneous measurements of neuronal activity and fMRI signals in the rat brain have shed new light on the origins of resting-state fMRI connectivity networks.

A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.

An analysis of author contribution statements in a large number of published papers reveals biases in the career trajectories of scientists.

A lexicon to help scientists and philosophers discuss the meaning of function in molecular biology more clearly is proposed.

Data are reported for the monthly number of uploads to and downloads from bioRxiv, and for the number of preprints that are later published in peer-reviewed journals.

An analysis of 31,873 clinical trials shows that adequate statistical power was most often present in trials with a male first author and a female last author.