A proposal for a complete cellular/network implementation of trial-and-error motor learning in the olivo-cerebellar system.

A combination of X-ray crystallography, molecular dynamics and small angle X-ray scattering shows that the transcription antiterminator M2-1 is a structurally dynamic homotetramer that undergoes large concerted conformational changes upon binding its target RNA.

Evolutionary graph theory solves the longstanding puzzle of why diverse infectious diseases and cancers show similar (approximately lognormal) distributions of their incubation periods.

MicroRNA-218 is required in both excitatory and inhibitory neurons of the developing hippocampus to regulate intrinsic and network excitability.

Bats' uniquely robust innate antiviral immune defenses select for faster transmitting viruses likely to generate extreme virulence upon spillover to secondary hosts with immune systems divergent from those of bat.

A combination of multicellular recording and optogenetic photostimulation was used to deeply characterize the spatial profiles and effective strengths of intralaminar and translaminar synaptic connections from genetically defined neuronal populations in the visual cortex of adult mouse.

Prevaccination levels of transcriptional modules related to monocytes, dendritic cells, and other immune categories correlate with clinical malaria risk in RTS,S/AS01E-vaccinated African children, suggesting that certain monocyte subsets may inhibit RTS,S/AS01E-induced protective responses.

Ecological and evolutionary perspectives are critical to understand, predict, prevent, and treat malaria parasites that may spread to humans from our close primate relatives.

Genomic approaches can be integrated with epidemiological and ecological studies to provide high-resolution answers to open questions about schistosomiasis transmission dynamics, offering a level of precision that is actionable, such that schistosomiasis-control programming can be tailored to regional contexts.

New mammarenaviruses have been identified from rodents in Cambodia and Thailand, and the Cardamones variant of Wēnzhōu virus has been found in Cambodian patients presenting with fever and respiratory symptoms.