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    1. Genetics and Genomics
    2. Neuroscience

    Genomic stability of self-inactivating rabies

    Ernesto Ciabatti, Ana González-Rueda ... Marco Tripodi
    SiR does not revert to wild type when produced in high-TEVp cell lines, is non-toxic in vivo, maintains transsynaptic spreading capabilities and revertant mutations do not accumulate during in vivo experiments.
    1. Neuroscience

    An open cortico-basal ganglia loop allows limbic control over motor output via the nigrothalamic pathway

    Sho Aoki, Jared B Smith ... Xin Jin
    A novel connection from ventral striatum to motor cortex enables emotion and motivation to influence action and motor control.
    1. Neuroscience

    No evidence from complementary data sources of a direct glutamatergic projection from the mouse anterior cingulate area to the hippocampal formation

    Lilya Andrianova, Steliana Yanakieva ... Michael T Craig
    A combination of anterograde and retrograde anatomical-tracing methods failed to provide evidence of a recently described projection from the anterior cingulate area to the hippocampus.
    1. Neuroscience

    Dopamine neurons projecting to the posterior striatum form an anatomically distinct subclass

    William Menegas, Joseph F Bergan ... Mitsuko Watabe-Uchida
    Dopamine neurons projecting to different targets receive a similar set of inputs, rather than forming reciprocal connections, whereas those projecting to the posterior striatum receive a distinct set of inputs.
    1. Neuroscience

    Coordinated head direction representations in mouse anterodorsal thalamic nucleus and retrosplenial cortex

    Marie-Sophie H van der Goes, Jakob Voigts ... Mark T Harnett
    Dual site recordings of mouse anterodorsal thalamic nucleus and retrosplenial cortex reveal near 0-ms lag between the head direction representations of the two regions after cue rotations and correlated drift in darkness.
    1. Neuroscience

    Diverse inhibitory projections from the cerebellar interposed nucleus

    Elena N Judd, Samantha M Lewis, Abigail L Person
    Inhibitory cerebellar feedback to the inferior olive is central to computational models of learning, but novel targets of these neurons identified here expand their potential roles.
    1. Neuroscience

    Cell type-specific long-range connections of basal forebrain circuit

    Johnny Phong Do, Min Xu ... Yang Dan
    Whole-brain mapping of the basal forebrain circuits reveals a connection diagram with highly convergent inputs and divergent outputs.
    1. Neuroscience

    Monosynaptic tracing maps brain-wide afferent oligodendrocyte precursor cell connectivity

    Christopher W Mount, Belgin Yalçın ... Michelle Monje
    Oligodendrocyte precursor cells receive brain-wide, circuit-specific intracortical, coritcocortical and thalamocortical synaptic inputs.
    1. Neuroscience

    Anatomical and physiological foundations of cerebello-hippocampal interaction

    Thomas Charles Watson, Pauline Obiang ... Laure Rondi-Reig
    Anatomical tracing and physiological recordings reveal neuronal pathways through which the cerebellum may influence hippocampal activity.
    1. Neuroscience

    Targeted anatomical and functional identification of antinociceptive and pronociceptive serotonergic neurons that project to the spinal dorsal horn

    Robert Philip Ganley, Marilia Magalhaes de Sousa ... Hanns Ulrich Zeilhofer
    Two populations of serotonergic neurons are present in the medial and lateral hindbrain, which are shown to project to distinct spinal cord regions and have opposing effects on nociception in mice.