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    1. Evolutionary Biology

    Rapid decline of bacterial drug-resistance in an antibiotic-free environment through phenotypic reversion

    Anett Dunai, Réka Spohn ... Csaba Pál
    Drug-resistance declines in the laboratory in an antibiotic stress-free environment, indicating that restricting antimicrobial usage in the clinics could be a useful policy.
    1. Evolutionary Biology

    Evolutionary consequences of nascent multicellular life cycles

    Jennifer T Pentz, Kathryn MacGillivray ... William C Ratcliff
    Clonal development, but not aggregation, promotes the transition of Darwinian individuality from cells to groups, emphasizing the fundamental role of initial multicellular life cycles in the evolution of multicellularity.
    1. Evolutionary Biology

    Evolutionary footprints of a cold relic in a rapidly warming world

    Eva Wolf, Emmanuel Gaquerel ... Marcus A Koch
    Evolutionary dynamics of polyploid plants of the genus Cochlearia during past periods of rapid climate change indicate increased rates of speciation and diversification in response to pronounced glacial cycles and cold periods in particular.
    1. Evolutionary Biology

    Zooanthroponotic transmission of SARS-CoV-2 and host-specific viral mutations revealed by genome-wide phylogenetic analysis

    Sana Naderi, Peter E Chen ... B Jesse Shapiro
    Several different mutations in the SARS-CoV-2 genome have occurred more times than expected by chance in either mink or deer infections, suggesting species-specific viral adaptations to these animals.
    1. Computational and Systems Biology
    2. Neuroscience

    Microsaccadic sampling of moving image information provides Drosophila hyperacute vision

    Mikko Juusola, An Dau ... Jouni Takalo
    New experiments and theory reveal how the ability to see image details depends upon photoreceptor function and eye movements, and how fruit flies (Drosophila) see spatial details beyond the optical limit of their compound eyes.
    1. Neuroscience

    Functional reallocation of sensory processing resources caused by long-term neural adaptation to altered optics

    Antoine Barbot, Woon Ju Park ... Geunyoung Yoon
    Chronic exposure to poor optical quality causes a functional reallocation of sensory processing resources that favors perceptual information less affected by the eye's optics.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy in co-cultured cancer cells

    Serkan Sayin, Brittany Rosener ... Amir Mitchell
    Mutations conferring resistance to Escherichia coli against the chemotherapy drug gemcitabine can have opposite effects on bacterial drug degradation and therefore can increase or decrease the chemotherapy load on neighboring cancer cells.
    1. Cell Biology

    Calcium-mediated actin reset (CaAR) mediates acute cell adaptations

    Pauline Wales, Christian E Schuberth ... Roland Wedlich-Söldner
    Calcium influx during acute cell stimulation triggers a global actin reset in mammalian cells, which is linked to plasma membrane repair and transcription and has implications for our understanding of cell migration, cancer, inflammation and cell stress response.
    1. Neuroscience

    Fine-scale computations for adaptive processing in the human brain

    Elisa Zamboni, Valentin G Kemper ... Zoe Kourtzi
    Laminar fMRI reveals that adaptive processing involves recurrent processing within visual cortex and top-down influences from posterior parietal cortex via feedback.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    High rates of evolution preceded shifts to sex-biased gene expression in Leucadendron, the most sexually dimorphic angiosperms

    Mathias Scharmann, Anthony G Rebelo, John R Pannell
    In the dioecious plant genus Leucadendron, shifts to sex-biased gene expression occurred predominantly in genes with ancestrally high rates of expression evolution, and were not correlated with morphology.