The lncRNA pCharme controls the expression of cardiomyocyte maturation genes and heart development by orchestrating the formation of MATR3-enriched nuclear condensates.

Micropatterned differentiation of human ESCs generates gastrulation cell types – germ layers, extraembryonic, and primordial germ cells with primate characteristics – that show conserved sorting behaviors when dissociated and reseeded as single-cell mixture.

Genetic lineage tracing approach combined with live imaging visualized the functional stem cell activity of Doublecortin-like kinase 1⁺ cells within pancreatic cancer in vivo.

A detailed molecular mechanism on lipid flipping from outside leaflet to the inside leaflet of the eukaryotic plasma membrane bilayer.

A combination of high-resolution structure determination, electrophysiology, and MD simulations reveal fundamental insight into the molecular function of voltage-gated chloride channels.

The sweet taste receptors in the cotton bollworm (Helicoverpa armigera) are evolved to adapt towards the larval and adult foods with different types and amounts of sugar.

Mean kurtosis brain maps, derived from a sub-diffusion model with a novel clinically feasible two-diffusion-time acquisition, exhibit superior tissue contrast compared to the traditional diffusional kurtosis imaging (DKI).

A single-nucleus transcriptomic atlas reveals the molecular signatures and trajectory dynamics of the neurogenic lineage in the human hippocampus during neonatal development, adulthood, aging, and after injury.

A combination of single-molecule and in vivo FRET showed how drugs affect conformation of mGluR2 at different domains.

Interhemispheric inhibition can be manipulated by directly and bidirectionally modulating the bilateral sensorimotor excitabilities in a spatially bivariate Brain-Computer Interface-based neurofeedback paradigm.