11,143 results found
    1. Neuroscience

    Cerebellar Purkinje cells control eye movements with a rapid rate code that is invariant to spike irregularity

    Hannah L Payne, Ranran L French ... Jennifer L Raymond
    Patterned optogenetic stimulation and analysis of neural activity provide convergent evidence that cerebellar Purkinje cells drive eye movements with a rapid rate code, without an additional contribution of spike irregularity.
    1. Epidemiology and Global Health

    Antigenic strain diversity predicts different biogeographic patterns of maintenance and decline of antimalarial drug resistance

    Qixin He, John K Chaillet, Frédéric Labbé
    A novel compartment model identifies the impact of malaria strain diversity on biogeographic drug resistance patterns, supported by empirical evidence.
    1. Neuroscience

    Implications of variable synaptic weights for rate and temporal coding of cerebellar outputs

    Shuting Wu, Asem Wardak ... Wade G Regehr
    Purkinje cell inputs onto cerebellar nuclei (CbN) neurons have highly variable strengths, which allow them to influence CbN firing in a graded manner, with the largest individual inputs effectively regulating both the rate and spike timing of CbN neuron firing.
    1. Epidemiology and Global Health

    Relationship between changing malaria burden and low birth weight in sub-Saharan Africa: A difference-in-differences study via a pair-of-pairs approach

    Siyu Heng, Wendy P O'Meara ... Dylan S Small
    A novel pair-of-pairs matching approach finds that community-level reductions in malaria burden can potentially substantially reduce the low birth weight rate in sub-Saharan Africa, particularly among firstborns.
    1. Neuroscience

    Multiplexed coding by cerebellar Purkinje neurons

    Sungho Hong, Mario Negrello ... Erik De Schutter
    Cerebellar Purkinje neurons use a multiplexed simple spike code combining synchrony/spike time and firing rate, with each component encoding distinct information about movements such as motion onset timing and kinematics.
    1. Neuroscience

    Model-based fMRI reveals dissimilarity processes underlying base rate neglect

    Sean R O'Bryan, Darrell A Worthy ... Tyler Davis
    Model-based imaging shows that the rostrolateral prefrontal cortex supports dissimilarity-based heuristics that people may use when they are confronted with ambiguous scenarios.
    1. Neuroscience

    Rate-distortion theory of neural coding and its implications for working memory

    Anthony MV Jakob, Samuel J Gershman
    The abstract framework of rate-distortion theory can be realized by a neural population coding model to reproduce key and previously unexplained regularities of human visual working memory.
    1. Epidemiology and Global Health

    Anopheles salivary antigens as serological biomarkers of vector exposure and malaria transmission: A systematic review with multilevel modelling

    Ellen A Kearney, Paul A Agius ... Freya JI Fowkes
    A systematic review with multilevel modelling quantified the positive association between human antibodies to Anopheles salivary proteins with Anopheles-human biting rate and epidemiological measures of malaria transmission, highlighting their potential as a tool to measure vector exposure and malaria transmission.
    1. Neuroscience

    Evaluating hippocampal replay without a ground truth

    Masahiro Takigawa, Marta Huelin Gorriz ... Daniel Bendor
    A novel tool enables cross-checking the quality of replay events and evaluating the effectiveness of a given replay detection method in the absence of a ground truth.
    1. Ecology

    Strong biomechanical relationships bias the tempo and mode of morphological evolution

    Martha M Muñoz, Y Hu ... SN Patek
    The rules of biomechanics consistently influence the tempo (rate) and mode (pattern) of evolution across four-bar linkage systems in animals.

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