1,305 results found
    1. Neuroscience

    Astrocyte and L-lactate in the anterior cingulate cortex modulate schema memory and neuronal mitochondrial biogenesis

    Mastura Akter, Mahadi Hasan ... Ying Li
    Astrocytic Gi pathway activation in the anterior cingulate cortex impairs schema memory and neuronal mitochondrial biogenesis, which can be rescued by exogenous L-lactate administration directly into the area.
    1. Plant Biology

    Prioritizing plant defence over growth through WRKY regulation facilitates infestation by non-target herbivores

    Ran Li, Jin Zhang ... Yonggen Lou
    A chewing herbivore induced WRKY transcription factor induces jasmonate-dependent defences and supresses gibbererellin-dependent growth, the latter of which renders rice plants more susceptible to secondary infestation by a piercing-sucking herbivore.
    1. Neuroscience

    Nucleus accumbens dopamine tracks aversive stimulus duration and prediction but not value or prediction error

    Jessica N Goedhoop, Bastijn JG van den Boom ... Ingo Willuhn
    The extracellular concentration of dopamine in the nucleus accumbens core is progressively diminished by white noise, an underutilized, easy-to-titrate aversive stimulus, but is unaffected by white-noise intensity, context valence, and associated probabilistic contingencies.
    1. Neuroscience

    Sequence action representations contextualize during rapid skill learning

    Debadatta Dash, Fumiaki Iwane ... Leonardo G Cohen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Physics of Living Systems

    Characterization of convergent thickening, a major convergence force producing morphogenic movement in amphibians

    David R Shook, Jason WH Wen ... Ray E Keller
    Xenopus embryos use tissue surface tension to generate hoop-stress around the blastopore to help close it during gastrulation.
    1. Microbiology and Infectious Disease

    Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of Toxoplasma gondii

    Alex Hunt, Matthew Robert Geoffrey Russell ... Moritz Treeck
    Partially overlapping functions of a limited subset of actin binding proteins allow the parasite Toxoplasma gondii to achieve actin regulation required for complex cellular processes.
    1. Cell Biology
    2. Neuroscience

    Action potential-coupled Rho GTPase signaling drives presynaptic plasticity

    Shataakshi Dube O'Neil, Bence Rácz ... Scott H Soderling
    Proteomic and genetic analysis discovers a new cytoskeletal mechanism of presynaptic short-term plasticity common across neuronal cell types.
    1. Evolutionary Biology

    Improved use of a public good selects for the evolution of undifferentiated multicellularity

    John H Koschwanez, Kevin R Foster, Andrew W Murray
    The ability to share resources for the benefit of all members of a group may have driven ancient organisms to evolve from a unicellular to a multicellular state.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The mitotic spindle protein CKAP2 potently increases formation and stability of microtubules

    Thomas S McAlear, Susanne Bechstedt
    Demonstration of the biochemical capacity of the spindle protein CKAP2 as the most potent assembly factor of microtubules.
    1. Stem Cells and Regenerative Medicine

    Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

    Sujeethkumar Prithiviraj, Alejandro Garcia Garcia ... Paul E Bourgine
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid

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