4 results found
    1. Biophysics and Structural Biology
    2. Human Biology and Medicine

    Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood

    Nicole Toepfner et al.
    The morphology and deformability of all blood cells can be measured continuously and with high throughput directly in whole blood without prior enrichment or separation.
    1. Biophysics and Structural Biology
    2. Cell Biology

    A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy

    Matthias Christoph Munder et al.
    The cytoplasm behaves as an adaptable fluid that can reversibly transition into a protective solid-like state upon stress.
    1. Cell Biology
    2. Neuroscience

    Piezo1 links mechanical forces to red blood cell volume

    Stuart M Cahalan et al.
    In red blood cells, the Piezo1 protein is responsible for sensing mechanical forces and volume regulation.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion

    Xavier Sisquella et al.
    Interaction of P. falciparum with the erythrocyte activates a phosphorylation cascade altering the viscoelastic properties of this area of the host membrane conditioning it for successful invasion.

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