Voice your concerns about research culture and research communication: Have your say in our 7th annual survey.
511 results found
    1. Immunology and Inflammation

    IL18 signaling promotes homing of mature Tregs into the thymus

    Cristina Peligero-Cruz et al.
    IL18R+ Tregs constitute a mature thymus-resident population, resistant to thymus involution and endowed with higher capacity to populate the thymus compared to their IL18R or IL18R deficient counterparts.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Hippocampal neural stem cells facilitate access from circulation via apical cytoplasmic processes

    Tamar Licht et al.
    Neural stem cells in the dentate gyrus have unique cytoplasmic processes that promote privileged access to circulating factors by a unique contact point with an endothelial cell.
    1. Immunology and Inflammation
    2. Neuroscience

    Drainage of inflammatory macromolecules from the brain to periphery targets the liver for macrophage infiltration

    Linlin Yang et al.
    Circulation of molecules from the brain can serve as a rapid mode of communication from the brain to the liver.
    1. Cell Biology
    2. Developmental Biology

    Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development

    Kasmir Ramo et al.
    The kinase JNK is required in endothelial cells for the development of native collateral arteries.
    1. Microbiology and Infectious Disease

    Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses

    Kathryn S Carpentier et al.
    The scavenger receptor MARCO and liver phagocytes are required for clearance of circulating alphavirus particles and thereby limit viremia and viral dissemination.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability

    Mark R Sullivan et al.
    The nutrients available in some tumors and the factors that influence tumor nutrient availability are characterized, which provides insight into the metabolic constraints of the tumor microenvironment.
    1. Physics of Living Systems

    Origin and role of the cerebrospinal fluid bidirectional flow in the central canal

    Olivier Thouvenin et al.
    The combination of data and modelling shows the mechanisms underlying bidirectional flow of cerebrospinal fluid and its impact on long range transport in the CSF between brain and spinal cord.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide

    Dominik Witzigmann et al.
    The combination of in vitro investigations, the zebrafish screening model and rodent experiments offered a unique approach to optimizing nanoparticles modified with Hepatitis B virus-derived peptides to specifically target hepatocytes.
    1. Cell Biology

    Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration

    Risheng Ye et al.
    Under insulinopenic conditions, the hormone adiponectin is essential for lipid uptake specifically in subcutaneous white adipose tissue, and is sufficient to ameliorate islet lipotoxicity.
    1. Microbiology and Infectious Disease

    Longitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognition

    Christine S Hopp et al.
    Malaria parasites enter the host via the skin, where they are inoculated by an infected mosquito as it probes for blood: the inoculation site is a bottleneck for the parasite and the only time when the parasite is extracellular for more than a few minutes, thus possibly presenting the best opportunity for antibody-mediated inhibition of infection.

Refine your results by:

Type
Research categories