367 results found
    1. Neuroscience

    TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro

    Hugo Balleza-Tapia et al.
    TrpV1 receptor activation rescues cognition-relevant network dynamics in mouse hippocampus in an acute Alzheimer disease model providing a novel therapeutic target.
    1. Genetics and Genomics

    Spliceosome factors target timeless (tim) mRNA to control clock protein accumulation and circadian behavior in Drosophila

    Iryna Shakhmantsir et al.
    Alternative splicing provides a mechanism to maintain oscillations of the circadian clock.
    1. Neuroscience

    Current and future goals are represented in opposite patterns in object-selective cortex

    Anouk Mariette van Loon et al.
    Multivoxel pattern of fMRI data reveals how the brain distinguishes between relevant and irrelevant representations as representations adapt to the order in which they are required in multiple task sequences.
    1. Stem Cells and Regenerative Medicine

    Long-term live imaging of the Drosophila adult midgut reveals real-time dynamics of division, differentiation and loss

    Judy Lisette Martin et al.
    A new platform for imaging live Drosophila adults yields vivid movies of the midgut over prolonged time scales, opening the door to the real-time study of organ renewal dynamics in a near-native context.
    1. Neuroscience

    Oxytocin-mediated social enrichment promotes longer telomeres and novelty seeking

    Jamshid Faraji et al.
    Social enrichment supports longevity.
    1. Cancer Biology

    Rejection of immunogenic tumor clones is limited by clonal fraction

    Ron S Gejman et al.
    A new, high-throughput in vivo MHC-I peptide minigene library platform shows that the naive immune system cannot eliminate cells presenting immunogenic antigens found at low frequencies within a growing tumor.
    1. Neuroscience

    Augmented reality powers a cognitive assistant for the blind

    Yang Liu et al.
    A non-invasive cognitive assistant for blind people endows objects in the environment with voices, allowing users to explore the scene, localize objects, and navigate through a building with minimal training.
    1. Neuroscience

    CA2 neuronal activity controls hippocampal low gamma and ripple oscillations

    Georgia M Alexander et al.
    Hippocampal area CA2 controls low gamma and ripple oscillations, brain waves known to be impaired in schizophrenia, implicating this important brain region in cognition.
    1. Neuroscience

    Macro-connectomics and microstructure predict dynamic plasticity patterns in the non-human primate brain

    Sean Froudist-Walsh et al.
    Brain recovery after injury can be predicted based on its activity and structure, which may allow us to understand why some brain injuries lead to permanent loss of cognitive function, while others do not.
    1. Ecology

    Meta-analysis challenges a textbook example of status signalling and demonstrates publication bias

    Alfredo Sánchez-Tójar et al.
    Meta-analysis takes down a textbook example in behavioural and evolutionary ecology, and demonstrates the existence of biases in the current scientific publishing culture.

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