7,408 results found
    1. Computational and Systems Biology

    Efficient coding in biophysically realistic excitatory-inhibitory spiking networks

    Veronika Koren, Simone Blanco Malerba ... Stefano Panzeri
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    A Memory Model of Rodent Spatial Navigation: Place Cells are Memories Arranged in a Grid and Grid Cells are Non-spatial

    David E Huber
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Evolutionary Biology
    2. Genetics and Genomics

    Broad-scale variation in human genetic diversity levels is predicted by purifying selection on coding and non-coding elements

    David A Murphy, Eyal Elyashiv ... Guy Sella
    Background selection is shown to be the dominant mode of linked selection in humans, with marked effects on diversity levels throughout autosomes.
    1. Neuroscience

    Visual homogeneity computations in the brain enable solving property-based visual tasks

    Georgin Jacob, Raghavendrarao T Pramod, Arun SP
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Solid
    • Incomplete
    1. Biochemistry and Chemical Biology

    A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion

    Xiao-Chuan Cai, Tuo Zhang ... Minkui Luo
    A chemical probe was characterized for potency, selectivity, and ability to alter CARM1-dependent epigenetic plasticity against cancer cell invasion.
    1. Biochemistry and Chemical Biology

    Decoding m6Am by simultaneous transcription-start mapping and methylation quantification

    Jianheng Fox Liu, Ben R Hawley ... Samie R Jaffrey
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Specific Sensitivity to Rare and Extreme Events: Quasi-Complete Black Swan Avoidance vs Partial Jackpot Seeking in Rat Decision-Making

    Mickaël Degoulet, Louis-Matis Willem ... Patrick A Pintus
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Genetics and Genomics
    2. Evolutionary Biology

    Inversions Can Accumulate Balanced Sexual Antagonism: Evidence from Simulations and Drosophila Experiments

    Christopher S McAllester, John E Pool
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Epidemiology and Global Health
    2. Medicine

    Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort

    ISARIC Clinical Characterisation Group, Matthew D Hall ... Piero L Olliaro
    Patient outcomes, and the time spent by patients during hospital admission, showed considerable variation over the first year of the COVID-19 pandemic.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Juxtaposition of heterozygous and homozygous regions causes reciprocal crossover remodelling via interference during Arabidopsis meiosis

    Piotr A Ziolkowski, Luke E Berchowitz ... Ian R Henderson
    Heterozygosity changes the balance between interfering and non-interfering crossovers during Arabidopsis meiosis.
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