Parenchymal astrocytes are quiescent neural stem cells whose neurogenic potential can be unleashed by targeted manipulations guided by single-cell RNA sequencing data.
Staff from the Mayo Clinic in the US and the Karolinska Institute in Sweden describe a joint transatlantic course intended to broaden the horizons of the next generation of researchers in the field of regenerative medicine.
Modular tetravalent antibodies can be engineered to stimulate signaling through any combination of Frizzled and LRP receptors to drive organoid growth and mobilize endogenous stem cells in vivo.
Bioinformatic analysis of mesenchymal stem cell chondrogenesis identified a novel long noncoding RNA, GRASLND, which suppresses interferon signaling and enhances chondrogenesis.
To understand how regeneration works across the different scales of living systems, we first need to identify the essential components underlying this process.
The turquoise killifish from ephemeral pools in African savannah combines extremely short lifespan with a standard vertebrate body plan – ideal attributes for a laboratory animal.
