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    1. Neuroscience

    Ultrastructural sublaminar-specific diversity of excitatory synaptic boutons in layer 1 of the adult human temporal lobe neocortex

    Astrid Rollenhagen, Akram Sadeghi ... Joachim HR Lübke
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    1. Neuroscience

    Pre-post synaptic alignment through neuroligin-1 tunes synaptic transmission efficiency

    Kalina T Haas, Benjamin Compans ... Eric Hosy
    Neuroligin 1 is a critical adhesion molecule which organizes AMPA receptor nanodomains in close vicinity to pre-synaptic release sites, and whose genetic or chemical disruption severely impairs synaptic transmission properties.
    1. Neuroscience

    Mesolimbic dopamine projections mediate cue-motivated reward seeking but not reward retrieval in rats

    Briac Halbout, Andrew T Marshall ... Sean B Ostlund
    Inhibiting ventral tegmental dopamine neurons, or their inputs to nucleus accumbens, disrupts cue-motivated reward seeking in a manner that depends on the microstructure of behavior.
    1. Ecology
    2. Microbiology and Infectious Disease

    Metapopulation ecology links antibiotic resistance, consumption, and patient transfers in a network of hospital wards

    Julie Teresa Shapiro, Gilles Leboucher ... Jean-Philippe Rasigade
    Patterns of antibiotic use and the connectivity between wards are independently associated with the incidence of antimicrobial-resistant infections in hospital networks.
    1. Neuroscience

    Coupling of pupil- and neuronal population dynamics reveals diverse influences of arousal on cortical processing

    Thomas Pfeffer, Christian Keitel ... Joachim Gross
    Spontaneous fluctuations in pupil-indexed arousal shape human cortical dynamics in a frequency-dependent and spatially diverse manner.
    1. Developmental Biology
    2. Neuroscience

    Pioneer neurog1 expressing cells ingress into the otic epithelium and instruct neuronal specification

    Esteban Hoijman, L Fargas ... Berta Alsina
    Quantitative 4D image analysis identifies a group of cells which enter into the otic primordium during morphogenesis and instructs neuronal specification.
    1. Stem Cells and Regenerative Medicine

    Live cell-lineage tracing and machine learning reveal patterns of organ regeneration

    Oriol Viader-Llargués, Valerio Lupperger ... Hernán López-Schier
    A combination of live cell tracking, cell-lineage tracing and machine learning shows that injured sensory organs repair accurately regardless of the extent of damage.
    1. Neuroscience

    Synaptic targets of photoreceptors specialized to detect color and skylight polarization in Drosophila

    Emil Kind, Kit D Longden ... Mathias F Wernet
    The fly connectome reveals dedicated cell types for processing specific kinds of visual information such as color or skylight polarization.
    1. Neuroscience

    Signal denoising through topographic modularity of neural circuits

    Barna Zajzon, David Dahmen ... Renato Duarte
    Topographic maps can gradually increase the fidelity of sensory representations and improve signal-to-noise ratio across multiple cortical circuits, a generic architectural feature that depends solely on the modularity of topographic projections and recurrent inhibition.
    1. Neuroscience

    Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain

    Julio D Perez, Nimrod D Rubinstein ... Catherine Dulac
    A subset of genes in the mouse brain show dynamically regulated and unequal expression of maternally and paternally derived variants, with implications for brain development and function.