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    1. Genetics and Genomics
    2. Neuroscience

    High neural activity accelerates the decline of cognitive plasticity with age in Caenorhabditis elegans

    Qiaochu Li et al.
    Chronic excitation of the Caenorhabditis elegans oxygen-sensing neurons alters calcium homeostasis to accelerate the decline of neural plasticity with age.
    1. Neuroscience

    Maternal cortisol is associated with neonatal amygdala microstructure and connectivity in a sexually dimorphic manner

    David Q Stoye et al.
    Prenatal stress is transmitted to infant development through cortisol, which imparts sex-specific effects on the development and connectivity of the amygdalae.
    1. Immunology and Inflammation

    Genetic timestamping of plasma cells in vivo reveals tissue-specific homeostatic population turnover

    An Qi Xu et al.
    A new system to genetically label and manipulate plasma cells in vivo in their microenvironment resolves current technical limitations and reveals tissue-specific homeostatic population turnover.
    1. Neuroscience

    Social dominance mediates behavioral adaptation to chronic stress in a sex-specific manner

    Stoyo Karamihalev et al.
    Social dominance has opposing effects on behavior following stress in male vs. female mice indicating an important role in sex differences in the stress response.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Alpha-satellite RNA transcripts are repressed by centromere–nucleolus associations

    Leah Bury et al.
    Single molecule FISH analysis defines the behavior of centromere-derived alpha-satellite transcripts in intact human cells and reveals a critical role for centromere-nucleolar contacts in repressing alpha-satellite transcription.
    1. Neuroscience

    The amygdala instructs insular feedback for affective learning

    Dominic Kargl et al.
    Hierarchical information flow in a cortico-limbic loop between the insular cortex, central amygdala and the cholinergic basal forebrain links bodily states with environmental stimuli to guide fear and reward behavior.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Repression of interrupted and intact rDNA by the SUMO pathway in Drosophila melanogaster

    Yicheng Luo et al.
    SUMO-dependent pathway is responsible for selective repression of damaged rDNA and silencing of intact surplus units revealing an epigenetic mechanism that controls the differential expression of identical sequences in the same cell.
    1. Neuroscience

    Robo functions as an attractive cue for glial migration through SYG-1/Neph

    Zhongwei Qu et al.
    An extracellular cleavage fragment of Robo released from neurons can bind to glia-expressed SYG-1 to guide glia migration.
    1. Plant Biology

    The genetic architecture of host response reveals the importance of arbuscular mycorrhizae to maize cultivation

    M Rosario Ramírez-Flores et al.
    Heritable variation in the benefit maize plants receive from arbuscular mycorrhizal fungi supports the feasibility of breeding crops to optimize use of this ancient symbiosis.
    1. Cell Biology
    2. Immunology and Inflammation

    Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells

    Elizabeth Rivers et al.
    WASp is an immunometabolic regulator of human myeloid cells and regulates autophagy and mitochondrial homeostasis.