Precisely-timed bursts of closed-loop vagus nerve stimulation during rehabilitation restore neural connectivity and substantially improve recovery of motor function after SCI.

A combined rehabitative protocol after stroke in the mouse normalizes transcallosal inhibition and promotes "true recovery" of forelimb motor function.

A genetically-defined population of spinal interneurons is reciprocally connected with spinal locomotor circuits and mediates recovery of locomotor function following spinal cord transection.

After complete spinal transection in adult rats, careful combinations of pharmacological and physical therapies create a novel cortical sensorimotor circuit that may bypass the lesion through biomechanical coupling, allowing animals to recover unassisted hindlimb locomotion.

Tonic disinhibition of left motor cortex during prism adaptation enhanced consolidation of sensorimotor and cognitive prism after effects, causing lasting clinical gains in three patient cases with chronic treatment-resistant visual neglect.

A series of experiments shows how muscle fatigue impairs motor-skill learning on subsequent practice days beyond its effects on task execution.

Hand somatotopy can be preserved in the primary somatosensory cortex of tetraplegic patients, despite the absence of sensorimotor function and periphery-brain communication, but deteriorates over years after injury.

A critical re-evaluation of some of the quintessential examples given as evidence for cortical reorganisation argues that, contrary to the prevalent view, any opportunities for functional change in cortical organisation are incremental and constrained by the underlying structural ‘blueprint'.

Acute intermittent hypoxia is a noninvasive approach that enhances corticospinal function in humans, likely through alterations in corticospinal-motoneuronal synaptic transmission.