A freely available computer program that takes into account specific local conditions enables users to predict the impact of adopting different diagnostic strategies on the spread of tuberculosis in their region.

Mathematical models of the build-up and depletion of the hypnozoite reservoir in the liver can inform the design of treatment strategies for preventing Plasmodium vivax relapse infections.

Deleterious mutations slow down flu's antigenic evolution, make it more punctuated in nature, and reduce the virus's genetic diversity.

Live intracellular bacterial pathogens can transfer from infected cells to uninfected macrophages upon cell-to-cell contact.

Endogenous virus sequences in the genomes of modern mammals reveal the global spread of an ancient virus lineage, including frequent interspecies transmission, adaptation, and emergence spanning several million years of mammalian evolution

The bacterium Chlamydia trachomatis, a human pathogen, hijacks its host’s energy supplies by using the parasitophorous vacuole as a glycogen synthesis and storage compartment.

Unlike other similar enzymes, the antimicrobial enzyme PlyC can interact with and translocate eukaryotic membranes, and then lyse and kill intracellular bacteria.

An innate immune system signaling pathway in planarians has a dual role: it enhances apoptosis during bacterial infection, but represses apoptosis during tissue regeneration in the absence of infection.

HMGB1 drives the development of paucigranulocytic asthma in RAGE deficient mice.

Under sustained malaria control in PNG, the incidence of distinct blood-stage infections quantifies heterogeneity in transmission, significantly predicting risk of both P. falciparum and P. vivax malaria episodes at a population and individual scale.