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    1. Neuroscience

    v-SNARE transmembrane domains function as catalysts for vesicle fusion

    Madhurima Dhara et al.
    Structural flexibility of the synaptobrevin-2 transmembrane domain promotes membrane fusion.
    1. Neuroscience

    Dopaminergic neurons write and update memories with cell-type-specific rules

    Yoshinori Aso, Gerald M Rubin
    Building on previous work (Aso et al., 2014a; Aso et al., 2014b), cell-type-specific drivers and optogenetics are used to control the local release of dopamine and reveal that distinct learning rules are implemented in parallel memory units.
    1. Neuroscience

    Extracting grid cell characteristics from place cell inputs using non-negative principal component analysis

    Yedidyah Dordek et al.
    Computational modeling of the brain’s navigation system reveals that place cells can drive the formation of hexagonal patterns experimentally observed in grid cells activity.
    1. Neuroscience

    Retroactive modulation of spike timing-dependent plasticity by dopamine

    Zuzanna Brzosko et al.
    Dopamine, a reward signal in the brain, can retroactively convert hippocampal synaptic depression into potentiation, suggesting an elegant biological solution to the distal reward problem.
    1. Ecology

    Extinction risk and conservation of the world’s sharks and rays

    Nicholas K Dulvy et al.
    One-quarter of the Chondrichthyes have an elevated risk of extinction, mainly as a result of overfishing.
    1. Neuroscience

    Enhancement of fear memory by retrieval through reconsolidation

    Hotaka Fukushima et al.
    Retrieval enhances fear memory through reconsolidation by activating calcineurin-induced protein degradation and CREB-mediated gene expression in amygdala, hippocampus, and mPFC.
    1. Evolutionary Biology
    2. Neuroscience

    Recalibrating timing behavior via expected covariance between temporal cues

    Benjamin J De Corte et al.
    Rats act as if they expect that the delays associated with temporal cues will covary due to a common causal factor.
    1. Physics of Living Systems
    2. Cell Biology

    Mechanical design principles of a mitotic spindle

    Jonathan J Ward et al.
    Precise control of microtubule architecture greatly increases the force that the spindle can exert on chromosomes.
    1. Neuroscience

    Odor-evoked category reactivation in human ventromedial prefrontal cortex during sleep promotes memory consolidation

    Laura K Shanahan et al.
    Odor cues in sleep evoke content-specific signatures of neural reactivation in visual and prefrontal brain areas that predict subsequent memory performance in the wake state.
    1. Neuroscience

    Motor context dominates output from purkinje cell functional regions during reflexive visuomotor behaviours

    Laura D Knogler et al.
    Purkinje cells of the cerebellum, a conserved vertebrate brain region important for sensorimotor integration, receive sensory and motor information from distinct input streams and are functionally clustered into modules reflecting the larval zebrafish's behavioral repertoire.