Browse the search results

Resetting a young gut microbiota in middle-aged individuals extends life span and slows aging in the naturally short-lived turquoise killifish, a new vertebrate model organism to study how the microbiota affects the aging process.

While acute senescence of decidualizing cells drives the inflammatory response underpinning uterine receptivity, subsequent clearance by activated natural killer cells transiently rejuvenates the cycling endometrium, enabling transition into a gestational tissue upon embryo implantation.

To promote longevity under heat stress shares yeast aging factors with progeny through a down-regulation of the diffusion barrier in the membranes between the mitotic cells.

Genetic analyses uncovered that the asymmetrically long non-coding RNA cherub is required for brain tumor growth.

The specification of tegumental progenitor cells in Schistosoma mansoni relies on a pair of flatworm-specific transcription factors that are related to genes regulating epidermal specification in free-living flatworms.

During aging, the pancreatic endocrine islets undergo chronic inflammation, which is associated with a reduced capacity for self-renewal of the insulin-producing beta-cells in zebrafish.

Morphological and functional rejuvenation upon exit from adult reproductive diapause in C. elegans is independent of germline signaling, but instead involves somatic nucleolar activation and expansion of the RNA pool.

Ploidy-increasing endocycles may represent a tradeoff between loss of regenerative capacity and preservation of tissue architecture.

Mitochondria morphology can be use to identify quiescent and senescent yeast cells.