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    1. Chromosomes and Gene Expression
    2. Plant Biology

    Widespread premature transcription termination of Arabidopsis thaliana NLR genes by the spen protein FPA

    Matthew T Parker, Katarzyna Knop ... Gordon G Simpson
    The expression of Arabidopsis NLR immune response genes is modulated by premature transcription termination, and this has implications for understanding NLR regulation and evolutionary dynamics.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Formicine ants swallow their highly acidic poison for gut microbial selection and control

    Simon Tragust, Claudia Herrmann ... Heike Feldhaar
    Poison acidified crops sanitize food and limit disease transmission while at the same time structuring the gut microbiota and thus contribute to the ecological and evolutionary success of formicine ants.
    1. Cell Biology
    2. Computational and Systems Biology

    Remote control of microtubule plus-end dynamics and function from the minus-end

    Xiuzhen Chen, Lukas A Widmer ... Yves Barral
    A mechanism for yeast centrosomes to differentiate the microtubule cytoskeleton.
    1. Ecology

    Harbouring public good mutants within a pathogen population can increase both fitness and virulence

    Richard J Lindsay, Michael J Kershaw ... Ivana Gudelj
    Cooperation theory and a novel synthetic infection system provides a mechanistic understanding of why a seemingly successful disease management strategy can have devastating consequences for infected hosts.
    1. Developmental Biology

    Notch-dependent and -independent transcription are modulated by tissue movements at gastrulation

    Julia Falo-Sanjuan, Sarah Bray
    Live-imaging of Notch-dependent transcription in vivo reveals that cell movements during gastrulation influence transcription levels, and do so downstream of Notch cleavage, illustrating the importance of crosstalk between mechanics and transcription in the context of embryonic development.
    1. Cell Biology

    Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore

    Evgeniya Trofimenko, Gianvito Grasso ... Christian Widmann
    Cationic cell-penetrating peptides (CPPs) enter cells through ~2 (–5)-nm-wide water pores induced by the strong negative plasma membrane potential that CPPs and the activity of potassium channels generate.
    1. Computational and Systems Biology
    2. Developmental Biology

    Unipolar distributions of junctional Myosin II identify cell stripe boundaries that drive cell intercalation throughout Drosophila axis extension

    Robert J Tetley, Guy B Blanchard ... Bénédicte Sanson
    Analysing Myosin II unipolar planar polarisation with high spatial and temporal resolution during Drosophila axis extension reveals how tissue boundaries drive polarized cell intercalation while limiting cell mixing.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Mechanistic theory predicts the effects of temperature and humidity on inactivation of SARS-CoV-2 and other enveloped viruses

    Dylan H Morris, Kwe Claude Yinda ... James O Lloyd-Smith
    Viruses, including SARS-CoV-2, retain infectivity longer at low temperatures and extreme relative humidities because these conditions slow down the chemical reactions that inactivate those viruses.
    1. Computational and Systems Biology
    2. Neuroscience

    FoxP2 isoforms delineate spatiotemporal transcriptional networks for vocal learning in the zebra finch

    Zachary Daniel Burkett, Nancy F Day ... Stephanie A White
    Basal ganglia gene coexpression patterns shift across the sensorimotor critical period for vocal learning.
    1. Neuroscience

    A distributed brain response predicting the facial expression of acute nociceptive pain

    Marie-Eve Picard, Miriam Kunz ... Pierre Rainville
    Facial expression provides a complementary channel to communicate pain experiences and reflects the activation of brain mechanisms partly distinct from those associated with subjective self-reports of pain.
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