6,296 results found
    1. Cancer Biology
    2. Human Biology and Medicine

    Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death

    Haley Hieronymus et al.
    The percentage of a tumor’s genome with alterations in copy number is correlated with increased mortality across a range of tumor types and can be measured using a clinically approved sequencing assay.
    1. Cell Biology

    Cyclin-dependent kinase control of motile ciliogenesis

    Eszter K Vladar et al.
    Cyclin-dependentkinase 2 (Cdk2), the master regulator of S phase events during the cell cycle, controls the earliest step in the motile ciliogenesis pathway in quiescent multiciliatedairway epithelial cells.
    1. Developmental Biology

    An intrinsic cell cycle timer terminates limb bud outgrowth

    Joseph Pickering et al.
    Size control in limbs is an intrinsically determined process.
    1. Developmental Biology
    2. Cell Biology

    Direct visualization of a native Wnt in vivo reveals that a long-range Wnt gradient forms by extracellular dispersal

    Ariel M Pani, Bob Goldstein
    Free, extracellular dispersal of Wnt proteins generates a long-range gradient during animal development and is required for signaling.
    1. Plant Biology

    Anisotropic growth is achieved through the additive mechanical effect of material anisotropy and elastic asymmetry

    Firas Bou Daher et al.
    Growing upwards in the young seedling is controlled by two cooperative mechanical mechanisms: cellulose orientation in inner tissues and differential elasticity in epidermal cells.

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