2,799 results found
    1. Developmental Biology

    Reorganization of the flagellum scaffolding induces a sperm standstill during fertilization

    Martina Jabloñski, Guillermina M Luque ... Mariano G Buffone
    The double helix actin network surrounding the mitochondrial sheath of the sperm midpiece undergoes structural changes prior to the motility cessation during sperm-egg fusion.
    1. Neuroscience

    De novo learning versus adaptation of continuous control in a manual tracking task

    Christopher S Yang, Noah J Cowan, Adrian M Haith
    Humans can rapidly build a new controller when learning continuous movement tasks and can flexibly integrate this process with adaptation of an existing controller.
    1. Immunology and Inflammation
    2. Neuroscience

    T cells modulate the microglial response to brain ischemia

    Corinne Benakis, Alba Simats ... Arthur Liesz
    Transcriptional signature and cell morphology of the stroke-associated microglia are reprogrammed by distinct T cell subpopulations.
    1. Neuroscience

    Phase separation of competing memories along the human hippocampal theta rhythm

    Casper Kerrén, Sander van Bree ... Maria Wimber
    The human brain uses a phase code to temporally segregate overlapping, competing memories along the phase cycle of the theta rhythm.
    1. Neuroscience

    Successor-like representation guides the prediction of future events in human visual cortex and hippocampus

    Matthias Ekman, Sarah Kusch, Floris P de Lange
    Early visual cortex (V1) and hippocampal cortex represent a predictive map of the visual world akin to the successor representation.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Lactoferricins impair the cytosolic membrane of Escherichia coli within a few seconds and accumulate inside the cell

    Enrico F Semeraro, Lisa Marx ... Georg Pabst
    The damage of the bacterial cell envelope is found to be only a secondary effect of the antimicrobial activity of lactoferricin derivatives.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Development of equation of motion deciphering locomotion including omega turns of Caenorhabditis elegans

    Taegon Chung, Iksoo Chang, Sangyeol Kim
    ElegansBot, a two-dimensional rigid body chain model, simulates various locomotion of C. elegans, including omega and delta turns, using Newtonian equations of motion.
    1. Microbiology and Infectious Disease

    Interplay between acetylation and ubiquitination of imitation switch chromatin remodeler Isw1 confers multidrug resistance in Cryptococcus neoformans

    Yang Meng, Yue Ni ... Chen Ding
    Isw1 acts as a master regulator in modulating the expression of drug-resistance genes, and this regulatory mechanism is dependent on the interaction of Isw1 acetylation and ubiquitination.
    1. Neuroscience

    Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing

    Leena Ali Ibrahim, Brie Wamsley ... Gordon Fishell
    RNA sequencing and conditional Nova mutants reveal that Nova protein function is necessary for activity-dependent alternative splicing of synaptic genes within somatostatin cortical interneurons and regulates its afferent and efferent connectivity.
    1. Neuroscience

    Cognitive regulation alters social and dietary choice by changing attribute representations in domain-general and domain-specific brain circuits

    Anita Tusche, Cendri A Hutcherson
    Regulatory success operates by goal-consistent increases and decreases of distinct attribute representations in generic neural hubs and in domain-specific brain regions, explaining when and why regulatory success generalizes across domains and contexts.

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