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Reproducibility in Cancer Biology: The challenges of replication
Interpreting the first results from the Reproducibility Project: Cancer Biology requires a highly nuanced approach.
Genetics and Genomics
Mosquitos: The taste of water
W Daniel Tracey
Female mosquitos require a specific ion-channel protein to sense the presence of fresh water in which they can lay their eggs.
Point of View: Four erroneous beliefs thwarting more trustworthy research
Mark Yarborough et al.
Strategies to improve public trust in biomedical research are being hindered by a scientific mindset that stifles interest in reform.
Structural Biology and Molecular Biophysics
Transcription: Overcoming chromatin barriers
Babette E de Jong, John van Noort
Single-molecule experiments reveal the dynamics of transcription through a nucleosome with single-base-pair accuracy.
Epidemiology and Global Health
Science Forum: Unit of analysis issues in laboratory-based research
Nick R Parsons et al.
A simulation study is used to demonstrate how mistakes in identifying the experimental unit and the unit of analysis can lead to incorrect analyses and inappropriate inferences when reporting research studies.
Peer Review: Decisions, decisions
Journals are exploring new approaches to peer review in order to reduce bias, increase transparency and respond to author preferences.
Human Biology and Medicine
Adverse Drug Reactions: The benefits of data mining
Audrey Bone, Keith Houck
Careful analysis of a database populated by physicians and patients sheds new light on the side effects of drugs.
Research: Theory, models and biology
Wenying Shou et al.
Theoretical ideas have a rich history in many areas of biology, and new theories and mathematical models have much to offer in the future.
Transport Proteins: Getting to grips with ammonium
Yi Wang, Jonathan A Javitch
Genetics and Genomics
Circadian Rhythms: Shedding new light on circadian clocks
Maud Demarque, Ueli Schibler
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