6,604 results found
    1. Epidemiology and Global Health
    2. Medicine

    A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib

    Valerie C Henderson et al.
    Preclinical efficacy experiments testing sunitinib in animal cancer models display a lack of methodological rigour, with trim-and-fill analysis suggesting prominent publication bias that leads to an overestimation of treatment effect.
    1. Cell Biology
    2. Developmental Biology

    Science Forum: Imaging methods are vastly underreported in biomedical research

    Guillermo Marqués et al.
    The poor reporting of imaging methods in the scientific literature is hindering the evaluation and replication of biomedical research.
  1. eLife Latest: Towards minimal reporting standards for life scientists

    A group of journal editors and experts in reproducibility and transparent reporting are putting together a framework for minimal reporting standards in the life sciences.
    1. Biochemistry and Chemical Biology

    How to measure and evaluate binding affinities

    Inga Jarmoskaite et al.
    Simple guidelines and a checklist are provided for performing high-quality equilibrium binding measurements.
    1. Neuroscience

    Inhibition stabilization is a widespread property of cortical networks

    Alessandro Sanzeni et al.
    The strongly coupled theoretical regime describes the function of mouse sensory and motor cortical areas.
    1. Neuroscience

    Creating and controlling visual environments using BonVision

    Gonçalo Lopes et al.
    BonVision is an open-source software for real-time rendering and control of 2D and 3D visual environments that also enables easy replication of experiments.
    1. Neuroscience

    Stimulus-dependent relationships between behavioral choice and sensory neural responses

    Daniel Chicharro et al.
    New stimulus-dependencies of choice-related signals in sensory neurons uncovered by new analytical results and methods.
    1. Neuroscience

    Cerebellar re-encoding of self-generated head movements

    Guillaume P Dugué et al.
    The cerebellum encodes self-generated head rotations in a head posture-dependent manner, providing in particular a representation of how the head rotates about axes referenced relative to gravity.
    1. Biochemistry and Chemical Biology
    2. Physics of Living Systems

    Optical estimation of absolute membrane potential using fluorescence lifetime imaging

    Julia R Lazzari-Dean et al.
    Fluorescence lifetime imaging microscopy, paired with fluorescent, voltage-sensitive dyes, provides a method for measuring and quantifying membrane potentials of living cells.
    1. Epidemiology and Global Health

    Opportunities for improved surveillance and control of dengue from age-specific case data

    Isabel Rodriguez-Barraquer et al.
    Age-specific incidence data, combined with mechanistic models of immunity, provides a unique opportunity to characterize disease transmission of dengue and other immunizing diseases at high temporal and spatial resolution.

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