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  1. Robots work on the underbody sealing of a 2015 Chrysler 200 inside the paint shop at Chrysler Group’s Assembly Plant

    Reproducibility: automated.

    Repurposing continuous integration tools for scientific analyses takes the headache out of reproducible research.
  2. Scientific Publishing: Transparent reporting of research results in eLife

    M Dawn Teare
    Manuscripts should include all the experimental and statistical details that are needed to replicate the experiments and analyses reported in them.
    Editorial
    Available as:
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  3. Point of View: Overflow in science and its implications for trust

    Sabina Siebert et al.
    Interviews with senior biomedical researchers reveal a perceived decline in trust in the scientific enterprise, in large part because the quantity of new data exceeds the field's ability to process it appropriately.
    1. Cancer Biology

    Reproducibility in Cancer Biology: Mixed outcomes for computational predictions

    Chi Van Dang
    Experimental efforts to validate the output of a computational model that predicts new uses for existing drugs highlights the inherently complex nature of cancer biology.
    Insight
    Available as:
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    1. Cancer Biology

    Reproducibility in Cancer Biology: Melanoma mystery

    Roger J Davis
    Biological variability has confounded efforts to confirm the role of PREX2 mutations in melanoma.
    Insight
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    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Reproducibility in Cancer Biology: Getting to grips with c-Myc

    Dirk Eick
    The transcription factor c-Myc amplifies the transcription of many growth-related genes in cancer cells, but its role as an oncogene is not fully understood.
    Insight
    Available as:
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    1. Cancer Biology

    Science Forum: Challenges in validating candidate therapeutic targets in cancer

    Jeffrey Settleman et al.
    More than 30 published articles have suggested that a protein kinase called MELK is an attractive therapeutic target in human cancer, but three recent reports describe compelling evidence that it is not.
  4. Point of View: Making the most of peer review

    Nikolai Slavov
    Journals should publish referee reports and respond to well-founded concerns about papers after publication.