Genetic analysis identifies an enzyme of the malaria parasite that is required to seal its host red blood cell membrane upon invasion, a key requirement of this important intracellular pathogen.

An analysis of more than 70,000 journal articles, including 5405 that were first released as a preprint on bioRxiv, shows that articles with a preprint received 49% more attention and 36% more citations than articles without one.

The malaria parasite uses an enzyme called GDPD to absorb choline, an important nutrient, from the bloodstream and this is essential for the parasite to survive inside the red blood cell.

The gut-released peptide oxyntomodulin mediates the alignment of liver clock gene and metabolic transcript rhythms with the timing of food intake by postprandial induction of hepatic Per gene expression.

Cutting-edge super-resolution microscopy methods reveal the architecture and dynamics of the sealing zone formed by human osteoclasts and composed of coordinated groups of podosomal cores encircled by adhesion complexes.

Advances in quantitative phase and polarized light microscopy, combined with deep learning, reveal the architecture of human brain tissue.

Information theory reveals that apparently similar signaling behaviors in ants and termites are instead governed by distinct communication protocols explaining their underlying different functions.

The regulation of the core transcription factor Oct4 by the Aurkb-PP1 axis links the cell cycle to pluripotency programs in embryonic stem cells.

The absence of a carboxy-terminal tail in the GnRH receptor is not required for the preovulatory luteinizing hormone surge and fertility in mammals.

The strength by which mouse B-cells bind surface-associated antigen determines how much their plasma membrane is permeabilized and also the extent of a resealing response involving lysosomal exocytosis, which promotes antigen extraction for intracellular processing and T-cell presentation.