Job insecurity is putting stress on early-career researchers in Australia, compromising their career development and potentially reducing the quality of research.

The San Francisco Declaration on Research Assessment (DORA) has developed a new tool called SPACE to support universities and institutions working to improve the assessment of research.

The majority of trials possess at least one characteristic that may compromise their ability to guide clinical practice.

Using unique data from five longitudinal UK birth cohorts, four distinct subsets of genetic variants were identified as differentially associated across wheezing phenotypes from infancy to adolescence with little evidence of genetic associations spanning across different phenotypes.

Current polygenic scores for education do not provide accurate predictions of educational achievement above other data or at the individual level.

Combined analyses of publicly available population-level variant data and detailed individual-level clinical data can be used to quantify the clinical impact of new SARS-CoV-2 variants in different settings.

A genome-wide association study using whole-genome sequencing data identifies the first known susceptibility genes for posterior urethral valves, the most common cause of kidney failure in boys, implicating the transcription factor TBX5 and planar cell polarity gene PTK7.

The coupling between neural oscillatory activity, haemodynamics, and metabolism is localised to the temporo-parietal region in response to social stimuli, providing evidence of the importance of investigating the energetic basis of brain functional specialisation.

The high rates of attrition that occur in drug development are widely regarded as problematic, but the failure of well-designed studies benefits both researchers and healthcare systems.

Affectionate touch in everyday life is linked to lower self-reported burden and is associated with higher endogenous oxytocin levels during times of prolonged stress.