Neural correlates of somatosensory target detection are restricted to secondary somatosensory cortex, whereas activity in insular, cingulate, and motor regions reflects stimulus uncertainty and overt reports.
Developing T cells whose TCRs have relatively low reactivity experience very brief TCR signaling events, experience delayed positive selection, and retaina preselection gene expression signature as they mature.
Antagonistic signaling by the kinases PI3K and Itpkb limits the kinetics and enforces the Notch-dependence of beta-selection – the most important cell-fate determining process in alpha beta T cell development.
Temperature and ionic conditions control the mechanical properties of virally encapsidated DNA and act as a switch between synchronized and desynchronized genome ejection dynamics in a phage population.
The Time Point Selection (or TPS) method is a general protocol for determining sampling rates for high throughout time series biological studies, that is efficient, cheap, scalable and works well for several different types of molecular data.