520 results found
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Dynamic subcellular localization of a respiratory complex controls bacterial respiration

    François Alberge et al.
    The localization of respiratory complexes in the cell membrane emerges as a critical factor for controlling respiration in bacteria.
    1. Microbiology and Infectious Disease

    Impaired respiration elicits SrrAB-dependent programmed cell lysis and biofilm formation in Staphylococcus aureus

    Ameya A Mashruwala et al.
    The absence of oxygen prompts Staphylococcus aureus cells to rupture resulting in increased formation of biofilms, which are the etiological agents of recurrent infections.
    1. Computational and Systems Biology
    2. Neuroscience

    CO2-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture

    David Forsberg et al.
    Novel brainstem organotypic cultures that generate rhythmic respiratory motor activity reveal the neural networks that control breathing and a new pathway in the hypercapnic response.
    1. Cancer Biology

    Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

    Lan-Feng Dong et al.
    A genetic approach documents that mitochondrial DNA moves from donor cells to recipient mtDNA-depleted cells in whole mitochondria and that this restores mitochondrial respiration and the capacity of the cells to form tumours.
    1. Neuroscience

    Interactions between respiratory oscillators in adult rats

    Robert TR Huckstepp et al.
    Active expiration in anesthetized rats is driven by the lateral parafacial region, but requires an additional form of excitation from another source.
    1. Neuroscience

    Species-specific modulation of food-search behavior by respiration and chemosensation in Drosophila larvae

    Daeyeon Kim et al.
    In naturalistic conditions, larvae of the Drosophila group exhibit species-specific strategies to search for food resources through a primitive form of risk-taking behavior that is controlled by a tradeoff between exploitation and odor-driven exploration.
    1. Neuroscience

    Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome

    Kerstin Ure et al.
    Genetically restoring Mecp2 expression only in GABAergic neurons in a mouse model of Rett syndrome improves inhibitory signaling, extends lifespan and rescues most but not all behavioral deficits.
    1. Microbiology and Infectious Disease

    Biofilms: Take my breath away

    Vinai C Thomas, Paul D Fey
    A lack of oxygen activates a pathway that causes the bacterial cell wall to break down, which, in turn, aids bacterial biofilm development.
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    1. Biochemistry
    2. Microbiology and Infectious Disease

    A unifying mechanism for the biogenesis of membrane proteins co-operatively integrated by the Sec and Tat pathways

    Fiona J Tooke et al.
    Bioinformatics and experimental approaches identify families of membrane proteins requiring the co-ordinated action of the Sec pathway and Tat pathways for their integration and define features of the polypeptides that mediate interaction with these pathways.
    1. Neuroscience

    Intraneural stimulation elicits discrimination of textural features by artificial fingertip in intact and amputee humans

    Calogero Maria Oddo et al.
    Delivering specific patterns of electrical activity to the median nerve of the arm triggers reliable sensations of texture, suggesting that it may ultimately be possible to restore complex tactile information to users of prosthetic limbs.

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