2 results found
    1. Developmental Biology
    2. Neuroscience

    Loss of Atoh1 from neurons regulating hypoxic and hypercapnic chemoresponses causes neonatal respiratory failure in mice

    Meike E van der Heijden, Huda Y Zoghbi
    Atoh1 promotes the development of two different neural circuits involved in hypoxic and hypercapnic respiratory responses that together are essential for neonatal respiratory drive and survival.
    1. Neuroscience

    The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO2

    Pierre-Louis Ruffault et al.
    The location of neurons responsible for increasing the breathing rate upon detecting elevated levels of CO2 in the blood has been pinpointed to the retrotrapezoid nucleus in the brainstem.

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