2,198 results found
    1. Neuroscience

    A dedicated visual pathway for prey detection in larval zebrafish

    Julia L Semmelhack et al.
    A subset of retinal ganglion cells respond specifically to small moving objects and project to a visual area that plays a key role in prey capture behavior.
    1. Cell Biology

    The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium

    Weiping Wang et al.
    The anaphase promoting complex (APC) has an essential role in ubiquitin-mediated proteolysis in the disassembly of cilia.
    1. Microbiology and Infectious Disease

    HIV in Women: How HIV exploits T cells in the endometrium

    Marta Rodriguez-Garcia
    Immune cells in the endometrium are targeted by HIV and re-programmed to allow them to survive and spread the virus throughout the body.
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  1. Meta-Research: Evaluating the impact of open access policies on research institutions

    Chun-Kai (Karl) Huang et al.
    A longitudinal study of open access levels at 1,207 research institutions worldwide reveals high performing institutions in Latin America, Africa and Asia.
    1. Structural Biology and Molecular Biophysics

    Intraflagellar Transport: Moving proteins along in the cilium

    Narcis Adrian Petriman, Esben Lorentzen
    The structures of the bovine and human BBSome reveal that a conformational change is required to recruit the complex to the ciliary membrane.
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    1. Computational and Systems Biology

    Meta-Research: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines

    Zeljana Babic et al.
    The use of Research Resource Identifiers (RRIDs) improves the proper use of cell lines in the biomedical literature.
  2. Meta-Research: How significant are the public dimensions of faculty work in review, promotion and tenure documents?

    Juan P Alperin et al.
    An analysis of review, promotion and tenure documents from 129 US and Canadian universities suggests institutions could better fulfill their public missions by changing how they incentivize the public dimensions of faculty work.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Point of View: Is cell size a spandrel?

    Ariel Amir
    Analysis of experiments on bacteria suggests that the dependence of cell size on growth rate is not an adaptation but a causal consequence of a regulatory mechanism that controls DNA replication.
  3. Point of view: Motivating participation in open science by examining researcher incentives

    Sarah E Ali-Khan et al.
    A survey of researchers at the Montreal Neurological Institute and Hospital provides insights into the challenges and opportunities involved in adopting an open science policy across an entire patient-oriented academic institution.
  4. Point of View: Competency-based assessment for the training of PhD students and early-career scientists

    Michael F Verderame et al.
    A method to assess the training of scientists, based on a set of 10 core competencies, is proposed.

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