1,277 results found
    1. Developmental Biology
    2. Neuroscience

    Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells

    So Goto et al.
    Neural retina-derived retinoic acids synthesized by Aldh1a1 control choroidal vascular development by regulating RPE-secreted VEGF.
    1. Genetics and Genomics
    2. Neuroscience

    Epigenomic landscapes of retinal rods and cones

    Alisa Mo et al.
    Genome-wide analysis of DNA methylation and accessible chromatin shows that retinal rods and cones have distinct epigenomic features that reflect differences in their development and function.
    1. Neuroscience

    Light-dependent pathways for dopaminergic amacrine cell development and function

    Teona Munteanu et al.
    Rods, not ipRGCs, are the major retinal photoreceptor impacting development of dopaminergic signaling in the retina.
    1. Developmental Biology

    Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development

    Shahram Jevin Poureetezadi et al.
    Prostaglandin synthesis and PGE2 receptor activity are essential for mediating segmentation of renal progenitors during pronephros formation in the zebrafish.
    1. Neuroscience

    Developmental Neuroscience: Catching a wave

    P Michelle Fogerson, John R Huguenard
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    1. Neuroscience

    Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact

    Thomas A Ray et al.
    Selective synapse formation in a retinal motion-sensitive circuit is orchestrated by starburst amacrine cells, which use homotypic interactions to initiate formation of a dendritic scaffold that recruits projections from circuit partners.
    1. Neuroscience

    Replacing the PDZ-interacting C-termini of DSCAM and DSCAML1 with epitope tags causes different phenotypic severity in different cell populations

    Andrew M Garrett et al.
    Mammalian Dscams require different intracellular interactions in different cell types during neural circuit formation to promote self-avoidance.
    1. Computational and Systems Biology
    2. Neuroscience

    The formation of the light-sensing compartment of cone photoreceptors coincides with a transcriptional switch

    Janine M Daum et al.
    Correlating changes in structure and gene expression in cone photoreceptors of mice daily, between birth and eye opening, created a resource that supports research in photoreceptor function, development, transplantation and repair.
    1. Neuroscience

    An excitatory cortical feedback loop gates retinal wave transmission in rodent thalamus

    Yasunobu Murata, Matthew T Colonnese
    The absence of functional inhibition is a developmentally transient circuit property of corticothalamic feedback that is essential for the central transmission of spontaneous retinal waves.
    1. Computational and Systems Biology
    2. Developmental Biology

    Dynamics and heterogeneity of a fate determinant during transition towards cell differentiation

    Nicolás Peláez et al.
    The maturation of multi-potent immature cells in the larval eye in Drosophila is regulated by a transcription factor that displays unexpected heterogeneous dynamics during the cells’ transitions towards differentiated states.

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