446 results found
    1. Neuroscience

    Evolution of neuronal anatomy and circuitry in two highly divergent nematode species

    Ray L Hong et al.
    The substrate for evolutionary divergence does not lie in changes in neuronal cell number or targeting, but rather in sensory perception and synaptic partner choice within invariant, prepatterned neuronal processes.
    1. Neuroscience

    Defined neuronal populations drive fatal phenotype in a mouse model of Leigh syndrome

    Irene Bolea et al.
    Glutamatergic brainstem neurons drive motor and respiratory deficits, and GABAergic basal ganglia neurons cause hypothermia and fatal epileptic events, in a model of mitochondrial disease.
    1. Neuroscience

    Frontal beta-theta network during REM sleep

    Sujith Vijayan et al.
    Two regions of the frontal lobe – the anterior cingulate cortex and, unexpectedly, the dorsolateral prefrontal cortex – show coordinated rhythmic activity during REM sleep.
    1. Neuroscience

    Secretagogin expression delineates functionally-specialized populations of striatal parvalbumin-containing interneurons

    Farid N Garas et al.
    In rodents and primates, there are two subtypes of parvalbumin-expressing interneurons that provide novel substrates for selective inhibition in the striatum.
    1. Developmental Biology
    2. Neuroscience

    Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain

    Kathryn C Allaway et al.
    Cholinergic populations with distinct cellular birthdates innervate deep versus superficial layers of the cortex with exquisite specificity.
    1. Neuroscience

    Alterations in the intrinsic properties of striatal cholinergic interneurons after dopamine lesion and chronic L-DOPA

    Se Joon Choi et al.
    HCN and SK channel currents in striatal cholinergic neurons are decreased with dopamine loss, but only HCN is restored by chronic L-DOPA and SK abnormality persists in dyskinesia.
    1. Neuroscience

    Peptidoglycan-dependent NF-κB activation in a small subset of brain octopaminergic neurons controls female oviposition

    Ambra Masuzzo et al.
    The universal bacteria cell wall component peptidoglycan impacts the egg-laying behavior of infected Drosophila females by directly modulating the activity of few brain octopaminergic neurons.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity

    Tamara M Sirey et al.
    Mitochondrial energy metabolism is post-transcriptionally regulated through an interplay between long and short non-coding RNAs.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Reciprocal regulation among TRPV1 channels and phosphoinositide 3-kinase in response to nerve growth factor

    Anastasiia Stratiievska et al.
    A dual-color TIRFM study reveals a new form of inflammatory regulation, in which a lipid kinase and ion channel reciprocally regulate each other to amplify the response to painful stimuli.
    1. Neuroscience

    Normal cognitive and social development require posterior cerebellar activity

    Aleksandra Badura et al.
    Social and cognitive functions require normal activity during development of the posterior cerebellum.

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